Inhibition of Tumor Promotion by Parthenolide: Epigenetic Modulation of p21
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چکیده
منابع مشابه
Inhibition of tumor promotion by parthenolide: epigenetic modulation of p21.
The promotion stage in the multistep process of epidermal tumorigenesis is NF-кB-dependent, epigenetically regulated, and reversible, thus, a suitable target for chemoprevention. We investigated whether the NF-кB inhibitor, parthenolide, currently in cancer clinical trials, attenuates tumor promotion by modulating the epigenetically regulated NF-кB target genes, p21 and cyclin D1. Parthenolide ...
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ژورنال
عنوان ژورنال: Cancer Prevention Research
سال: 2012
ISSN: 1940-6207,1940-6215
DOI: 10.1158/1940-6207.capr-12-0230